Tech entrepreneur and anti-aging evangelist Bryan Johnson is gearing up for considered one of his wildest stunts but.
Johnson introduced the plan on X, revealing he’ll devour 5.24 grams of dried psilocybin mushrooms, which include a lab-confirmed 28 milligrams of lively psilocybin, throughout a six-hour livestream on Sunday, March 30 at 10 a.m. PST. He referred to as the undertaking his second psychedelic trial in a three-month sequence and “the most quantified psychedelic experiment in history.”
Johnson emphasised that the livestream is totally medicalized and never meant to encourage copycat habits.
“Do not try this at home,” he wrote, stressing that the session will happen in a authorized setting with knowledgeable facilitator and medical supervision. He warned that psilocybin stays unlawful in lots of areas and carries “real medical and psychological risks.”
He additionally pushed again towards the concept that merely weighing mushrooms is sufficient to perceive efficiency. According to Johnson, two identical-looking 5-gram servings can differ wildly in power, anyplace from 20mg to greater than 60mg of psilocybin, relying on pressure, rising situations, and particular elements of the harvest.
“Without a lab test, you don’t know what dose you’re taking,” he wrote. He famous that his 28mg dosage is simply 2 mg shy of a ‘heroic dose,’ which medical research sometimes benchmark round 30mg.
During the livestream, Johnson will monitor 249 biomarkers, drawing 29 vials of blood and capturing knowledge from mind scans, urine, stool, saliva, fertility metrics, and multi-omics profiling — together with DNA, epigenetics, hormones, microbiome exercise, proteins, and cognitive perform. Multiple “biological age” metrics may even be analyzed, reminiscent of telomere size and mind getting older markers.
Johnson claims rising analysis suggests psilocybin could have potential longevity advantages, citing research tying the compound to decreased irritation, improved neuronal safety, elevated mind entropy, enhanced cognition, and longer lifespan in sure lab fashions.
Johnson’s stream is ready to characteristic visitor appearances from Grimes, who will carry out a stay DJ set, alongside psychedelic professional Hamilton Morris and enterprise capitalist Steve Jurvetson, who will focus on analysis surrounding psychedelics. Johnson additionally mentioned MrBeast, Naval Ravikant, Marc Benioff, and David Friedberg will “check in on me during the experience.” Moderation duties will fall to goth influencer Kate Tolo and journalist Ashlee Vance.
The billionaire, finest identified for his relentless anti-aging protocol, closed his announcement with a attribute mixture of bravado and humor: “Come watch me trip balls.”